Farrell was held as England captain recently by lead trainer Eddie Jones, regardless of not playing since November due to a lower leg issue.
He had would have liked to return against London Irish in the Challenge Cup on Sunday yet has now been precluded.
Britain play Scotland on Saturday, 5 February.
Farrell will see an expert ahead of schedule one week from now and is currently not relied upon to get together with England in their instructional course in Brighton.
Britain will declare a crew update on Monday with Courtney Lawes top choice to assume control over the captaincy in Farrell’s nonattendance.
Owen Farrell experienced a physical issue in preparing this week on top of things against London Irish, administering him out of the match, said Saracens in an assertion.
Owen was back in full preparing having recuperated from the lower leg injury he supported against Australia during the Autumn internationals.
We will have a further update after he sees an expert ahead of schedule one week from now.
With Farrell’s contribution for the beginning of the competition, at any rate, in question, Marcus Smith will be shared with run England’s assault from fly-half in the wake of intriguing during the November Tests.
Joe Marchant, Henry Slade and Mark Atkinson are among the middle choices accessible to Jones, while in-structure Leicester 10 George Ford could now win a review notwithstanding being surplus to necessities through the pre-winter.